Download Free Filoviruses PDF by Jens Kuhn Full Book and published by Springer Science & Business Media. This book was released on 2008-05-29 with total page 413 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the first comprehensive review of the world literature on filovirus research and provides the most extensive bibliography of the subject yet published. There is special emphasis on foreign literature that has never been summarized. Every aspect of filovirus research, including their history, epidemiology, clinical picture, pathology, molecular biology, and political aspects are reviewed in detail.
Download Free Biology and Pathogenesis of Rhabdo- and Filoviruses PDF by Asit K Pattnaik Full Book and published by World Scientific. This book was released on 2014-12-30 with total page 640 pages. Available in PDF, EPUB and Kindle. Book excerpt: Rhabdoviruses and Filoviruses are single-stranded, non-segmented, negative-strand RNA viruses, many of which cause significant morbidity and mortality in humans and animals. Certain members of these virus families have been used as excellent model systems to understand the molecular biology of replication, host responses to infections, and viral countermeasures. Rhabdoviruses have also been used as vaccine vectors as well as oncolytic agents. Studies on Filoviruses have now provided significant insights into how they enter susceptible cells, replicate and cause disease, and also how they evade the host's immune mechanisms. This book addresses the most recent findings on Rhabdovirus and Filovirus structure, replication mechanisms, host cell responses to virus infections and viral countermeasures. Chapters on emerging viruses as well as approaches for therapeutic interventions have also been included. This book represents an authoritative text that brings together the most recent advances on the cellular and molecular biology of Rhabdo- and Filoviruses, including mechanisms of pathogenesis. Contents:Overview of Rhabdo– and Filoviruses (Asit K Pattnaik and Michael A Whitt)Rhabdovirus Structure (Ming Luo)The Pathway of VSV Entry into Cells (Shem Johnson and Jean Gruenberg)Rhabdovirus Glycoproteins (Yves Gaudin and Michael A Whitt)VSV RNA Transcription and Replication (Jacques Perrault)Host Cell Functions in Vesicular Stomatitis Virus Replication (Phat X Dinh, Anshuman Das, and Asit K Pattnaik)Cytopathogenesis of Rhabdoviruses (Douglas S Lyles)Assembly and Budding of Rhabdo– and Filoviruses (Ziying Han and Ronald N Harty)Rhabdoviruses as Vaccine Vectors: From Initial Development to Clinical Trials (John K Rose and David K Clarke)Oncolytic Rhabdoviruses (Nicole E Forbes and John C Bell)Use of Rhabdoviruses to Study Neural Circuitry (Melanie Ginger, Guillaume Bony, Matthias Haberl, and Andreas Frick)Evolution of Rhabdo– and Filoviruses (Isabel S Novella, John B Presloid, and R Travis Taylor)Emerging Rhabdoviruses (Imke Steffen and Graham Simmons)Rabies Virus Replication and Pathogenesis (Andrew W Hudacek and Matthias J Schnell)Activation and Evasion of Innate Immune Response by Rhabdoviruses (Karl-Klaus Conzelmann)Rabies Virus Vaccines (Ying Huang, Clement W Gnanadurai, and Zhen F Fu)Filovirus Structure and Morphogenesis (Timothy F Booth, Daniel R Beniac, Melissa J Rabb, and Lindsey L Lamboo)Epidemiology and Pathogenesis of Filovirus Infections (Logan Banadyga and Hideki Ebihara)Filovirus Entry into Susceptible Cells (Rohit K Jangra, Eva Mittler, and Kartik Chandran)Filovirus Transcription & Replication (Kristina Brauburger, Laure R Deflubé, and Elke Muhlberger)Innate Immune Evasion Mechanisms of Filoviruses (Christopher F Basler, Gaya K Amarasinghe, and Daisy W Leung)Vaccines and Antivirals for Filoviruses (Chad E Mire and Thomas W Geisbe) Readership: Investigators, graduate students, and post-graduate researchers in the field of RNA virology. Key Features:The book describes the most recent advances in our understanding of cellular and molecular aspects of replication and pathogenic mechanisms of these two important viral pathogensUnlike other existing textbooks published earlier, this book brings together several major topics of research such as replication, host response to viral replication and viral countermeasures, viral evolution and emerging viruses, viral vectors, vaccines and antivirals, etcThe chapters in the book are written by renowned researchers in these fieldsKeywords:Negative-Strand RNA Virus;Mononegavirales;Rhabdovirus;Filovirus;VSV;Rabies Virus;Marburg Virus;Ebola Virus;Replication and Transcription;Virus Structure;Viral Pathogenesis;Epidemiology;Virus Entry;Virus Assembly and Budding;Cytopathogenesis;Neuronal Tracers;Viral Vectors;Oncolytic Viruses;Evolution;Emerging Viruses;Innate Immune Responses;Vaccines;Antivirals
Download Free Handbook of Viral Bioterrorism and Biodefense PDF by E. de Clercq Full Book and published by Elsevier. This book was released on 2003-04-17 with total page 162 pages. Available in PDF, EPUB and Kindle. Book excerpt: The atrocities of 11 September 2001 and the more recent casualties due to anthrax bioterrorism have dramatically emphasized the potential danger of biological warfare and bioterrorism. The editors of "Antiviral Research" have taken the initiative to edit a special issue of the Journal, focusing on Viral Bioterrorism and Biodefense. It is the first time in history that a special volume has been dedicated to this topic, which in view of the current circumstances is timely, appropriate and relevant. To what extent could viruses be "weaponized", i.e. turned into biological weapons, and used for biowarfare, which viruses would lend themselves for this purpose, how should we estimate the risk and the consequences, which diagnostic measures should be taken, and how should we react prophylactically, and, if needed, therapeutically?
Download Free Ebola and Marburg Viruses PDF by Elena Ryabchikova Full Book and published by Not Applicable. This book was released on 2004 with total page 242 pages. Available in PDF, EPUB and Kindle. Book excerpt: Electron microscopy has a special place among the wide range of techniques available for viral research. With electron microscopy, a virologist can follow the course of viral infections by visualizing cell damage and viral replication. Each virus family has its own structural and functional attributes, but attention is usually focused on the pathogenic and health-threatening viruses. The Ebola and Marburg filoviruses are notorious among these. The work was done at Vector in Novosibirsk, Russia, by Dr. Ryabchikova. Dr. Price has made it possible for Dr. Ryabchikova to explain her experiments and insights by expanding the descriptions and making the book readable by professionals who are not steeped in the intricacies of virology. In the course of writing this book, Dr. Price has incorporated more complete references of work done by other laboratories so that the story of the filoviruses is a compilation of the research done internationally, but told from the Russian perspective. In Ebola and Marburg Viruses: A View of Infection Using Electron Microscopy, the authors combine recent published and unpublished literature with the insight developed in over 30 years in electron microscopy and 15 years in virology to tell the story of filoviruses and how they invade and conquer their hosts. The book describes the dynamic properties of these viruses, follows the stages of filoviral infection from the individual cell to the whole organism, and reconstructs the sequential events that occur in filoviral infections. The book also demonstrates that, rather than a curiosity, the electron micrograph is an integral tool in studies of viral infection and the pathological process. Ebola and MarburgViruses: A View of Infection Using Electron Microscopy includes over 100 outstanding electron micrographs of filoviruses and the cell and tissue damage they cause during infection. Ebola and Marburg Viruses: A View of Infection Using Electron Microscopy is addressed to investigators in the widely diversified fields of medicine and biology. For this reason, Ryabchikova and Price have carefully elucidated concepts familiar to virologists that may be unfamiliar to nonvirolgists. The book is also designed to provide opportunities for investigators specializing in viruses to correlate their findings with the work of electron microscopists.
Download Free Emerging Challenges in Filovirus Infections PDF by Samuel Ikwaras Okware Full Book and published by BoD – Books on Demand. This book was released on 2020-02-12 with total page 106 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses the emerging challenges of the filovirus infections Ebola and Marburg virus disease. It reviews the complex ecology and role played by bats and other suspected intermediate hosts, including pigs. Also examined are the challenges for other modes of transmission and early diagnosis and detection. The immunology and pathogenesis of the infections and the impact on the host?s immune systems are discussed. The rare occurrence of Marburg virus infection in pregnancy and the long-term consequences of sexual transmission by survivors is further examined. These discussions have the potential to support future management of outbreaks and guide research for vaccines and medication for Ebola and Marburg disease.
Download Free Marburg- and Ebolaviruses PDF by Elke Mühlberger Full Book and published by Springer. This book was released on 2017-12-23 with total page 460 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides an overview of recent advances in our understanding of the biology of marburg- and ebolaviruses. It focuses on four essential areas: 1) ecology, outbreaks and clinical management, 2) disease, pathogenesis and protection, 3) virus replication inside the cell, and 4) molecular tools for virus study and taxonomy. For 50 years, these viruses have spilled over sporadically and without warning from their wildlife reservoirs, often causing major outbreaks and high fatalities. The consequences can be devastating, with a clear potential for global reach, as demonstrated by the 2013 West African outbreak of Ebola virus, which led to over 28,000 reported cases across three continents and more than 11,000 deaths. Given the international threat posed by these viruses, the pace and scope of basic research have also greatly intensified, ranging from studies of virus emergence, epidemiology, antiviral countermeasures and human disease to detailed mechanistic studies of virus entry, replication, virion assembly and protein structure. Written by internationally respected experts, this book will appeal to a wide audience and be a valuable resource for basic researchers, clinicians and advanced students alike.
Download Free Viruses and Human Disease PDF by Ellen G. Strauss Full Book and published by Elsevier. This book was released on 2002-03-12 with total page 383 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the first text to examine the connection between virology and human disease. It is also the first book to integrate basic virology with pathophysiological conditions. By contrast, most virology textbooks focus on the molecular biology involved without adequate reference to physiology. Viruses and Human Disease is four-color throughout and contains clearly labeled figures and tables. Key Features *Provides a concise overview of animal viruses, emphasizing those causing diseases in humans; * Integrates discussion of molecular biology, epidemiology, and the history of human viruses; * Presents treatment of prions, gene therapy, and vaccine development; * Illustrated in color by an expert virologist; * Includes world maps depicting the current distribution of existing and newly emerging viruses
Download Free Pseudotyped Viruses PDF by Youchun Wang Full Book and published by Springer Nature. This book was released on 2023-04-16 with total page 355 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book intends to report the new progress of pseudotyped viruses, including the construction of pseudotyped viruses with different strategies or vectors for most important viruses. Especially for emerging viruses, optimization of the condition and parameters for assay development based on the pseudotyped viruses and widely application as surrogate of authentic virus to study the biological functions of virus, detection of neutralizing antibody, screening viral entry inhibiters, and others. It includes most pseudotyped viruses that have the protein of the target virus on the surface of the parent virus with incomplete genome. The book is likely to be of interest to all researchers in the field of virology, vaccine, and anti-viral drug development and evaluation.
Download Free Mononegavirales: Advances in Research and Application: 2011 Edition PDF by Full Book and published by ScholarlyEditions. This book was released on 2012-01-09 with total page 20 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mononegavirales: Advances in Research and Application: 2011 Edition is a ScholarlyPaper™ that delivers timely, authoritative, and intensively focused information about Mononegavirales in a compact format. The editors have built Mononegavirales: Advances in Research and Application: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Mononegavirales in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Mononegavirales: Advances in Research and Application: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Download Free Receptor-independent/-associated viral tropism PDF by Akio Adachi Full Book and published by Frontiers E-books. This book was released on with total page 97 pages. Available in PDF, EPUB and Kindle. Book excerpt: One of the most important and outstanding characteristics of viruses is their cellular and host tropism. As parasitic entities, viruses have to compromise with numbers of positive and negative factors present in target cells for their survival. In the absence of an appropriate interaction with cells, they do not replicate at all. Viral tropism can be therefore determined at each replication step, from the entry to progeny production in target cells. There are two major types of viral tropism, that is, the receptor-dependent and -independent tropisms. Restriction of viral replication occurs on the cell surface (receptor-dependent viral entry step) and/or intracellularly (receptor-independent post-entry replication steps). Viruses have acquired some mechanisms through adaptive mutations and/or recombinations to counteract a wide variety of cellular restriction factors, or to correctly interact with numerous cellular factors necessary for replication. They thereby can replicate, spread and survive in certain cell lineages, tissues, organs and finally in host individuals. This evolutional process/pressure would have generated profound effects on the biological properties of viruses. Recently, many cellular anti-viral factors with unique action mechanisms in addition to co-viral factors have been discovered by extensive studies on molecular genetics of viruses. Researches of these factors would lead to the effective clinical applications, as well as the increase of basic biological knowledge. In this Research Topic, we focus on the receptor-independent and uniquely associated viral tropism other than the strictly receptor-dependent or -mediated one. By presenting a series of centered articles, we describe here the unique properties of various virus species. Any types of the tier 1 article would be accepted and included in this Topic.
Download Free Congenital and Perinatal Infections PDF by Jennifer S. Read Full Book and published by Oxford University Press. This book was released on 2018 with total page 345 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Infectious diseases that specifically target the developing fetus and newborn infant represent a special category with unique management challenges. This book provides state-of-the-art information on epidemiology, pathogenesis, diagnosis, treatment, and prevention of the most important viral, bacterial and parasitic pathogens that are transmitted from mother to infant"--Provided by publisher.
Download Free Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases E-Book PDF by John E. Bennett Full Book and published by Elsevier Health Sciences. This book was released on 2014-09-02 with total page 5094 pages. Available in PDF, EPUB and Kindle. Book excerpt: After thirty five years, Mandell, Douglas, and Bennett’s Principles and Practice of Infectious Diseases, 8th Edition is still the reference of choice for comprehensive, global guidance on diagnosing and treating the most challenging infectious diseases. Drs. John E. Bennett and Raphael Dolin along with new editorial team member Dr. Martin Blaser have meticulously updated this latest edition to save you time and to ensure you have the latest clinical and scientific knowledge at your fingertips. With new chapters, expanded and updated coverage, increased worldwide perspectives, and many new contributors, Mandell, Douglas, and Bennett’s Principles and Practice of Infectious Diseases, 8th Edition helps you identify and treat whatever infectious disease you see. Get the answers to any questions you have with more in-depth coverage of epidemiology, etiology, pathology, microbiology, immunology, and treatment of infectious agents than you’ll find in any other ID resource. Apply the latest knowledge with updated diagnoses and treatments for currently recognized and newly emerging infectious diseases, such as those caused by avian and swine influenza viruses. Put the latest knowledge to work in your practice with new or completely revised chapters on Influenza (new pandemic strains); New Middle East Respiratory Syndrome (MERS) Virus; Probiotics; Antibiotics for resistant bacteria; Antifungal drugs; New Antivirals for hepatitis B and C; Clostridium difficile treatment; Sepsis; Advances in HIV prevention and treatment; Viral gastroenteritis; Lyme Disease; Helicobacter pylori; Malaria; Infections in immunocompromised hosts; Immunization (new vaccines and new recommendations); and Microbiome. Benefit from fresh perspectives and expanded global insights from an expanded team of American and International contributors. Martin Blaser, MD, a leading expert and Muriel G. and George W. Singer Professional of Translational Medicine at New York University School of Medicine, joins veteran PPID editors John E. Bennett, MD, and Raphael Dolin, MD to continue a legacy of excellence. Find and grasp the information you need easily and rapidly with newly added chapter summaries.
Download Free Environmental Tracking for Public Health Surveillance PDF by Stanley A. Morain Full Book and published by CRC Press. This book was released on 2012-09-25 with total page 480 pages. Available in PDF, EPUB and Kindle. Book excerpt: Satellite imagery and data are widely used in public health surveillance to provide early warning of disease outbreaks and for averting pandemics. Convergence of these technologies began in the 1970s and has gained wide acceptance in the 21st Century. Environmental Tracking for Public Health Surveillance focuses on the expanding use of satellite sensor imagery and long-term spectral measurements for assessing and modelling Earth’s environments in context of public health surveillance. It addresses vector-borne, air-borne, water-borne, and zoonotic diseases, and explores analytical methods for forecasting environmental conditions and their potential for consequent disease outbreaks. Infectious and contagious diseases are of particular interest in this volume because once parasite-vector-human host pathways are triggered by favourable biological circumstances, pandemic diseases can spread to global scale in a matter of hours. The chapters advance readers through three sets of material. Part I reviews the 1970-2012 history of satellite Earth-science surveillance technology that led to linking natural environments to human diseases, and more generally to public health applications. Part II describes specific infectious and contagious diseases and the threat of emerging and re-emerging diseases. Part III explores the kinds of satellite data, modelling, and electronic information systems being developed to expedite health intercessions and responses at local to regional and global scales of reference. Equally important are the extensive reference sections for chapters in Parts II and III. For readers interested in tracking the development of Earth-science technology, these constitute a thorough entrée to both the health and environmental literature. The chapters are written jointly by experts in both the health and Earth-science technologies. Each chapter is accompanied by an extensive list of citations to provide background and validation of the current state-of-the-art for a variety of high-interest human diseases and associated health and well-being issues. The importance of day-to-day weather patterns, the impacts of severe weather events and longer-term climate cycles form the basis for developing information systems that meet goals and expectations of national and international health monitoring bodies. Environmental Tracking for Public Health Surveillance provides a state-of-the-art overview on how environmental tracking data from satellite, airborne, and ground-based sensors are being integrated into appropriate geophysical and spatial information system models to enhance public health surveillance and decision-making from local to global levels, and is intended primarily for a cross-disciplinary professional audience consisting of public health decision-makers, spatial data analysts, modelers, Earth observation specialists, and medical researchers.
Download Free Bats and Viruses PDF by Lin-Fa Wang Full Book and published by John Wiley & Sons. This book was released on 2015-09-08 with total page 402 pages. Available in PDF, EPUB and Kindle. Book excerpt: Approximately 75% of emerging infectious diseases are zoonoses, and the rate of emergence of zoonotic diseases is on the rise. Bats are being increasingly recognised as an important reservoir of zoonotic viruses of different families, including SARS coronavirus, Nipah virus, Hendra virus and Ebola virus. Understanding bats’ role in emerging zoonotic diseases is crucial to this rapidly expanding area of research. Bats and Viruses: A New Frontier of Emerging Infectious Diseases provides an updated overview of research focusing on bat biology and the role bats play as hosts of many major zoonotic viruses. The text covers bat biology, immunology, and genomics. Chapters also delve into the various major bat-borne virus families, including lyssaviruses, paramyxoviruses, coronaviruses, filoviruses and reoviruses, among others. Edited by leaders in the field, Bats and Viruses: A New Frontier of Emerging Infectious Diseases is a timely, invaluable reference for bat researchers studying microbiology, virology and immunology, as well as infectious disease workers and epidemiologists, among others.
Download Free Bats and Human Health PDF by Lisa A. Beltz Full Book and published by John Wiley & Sons. This book was released on 2017-12-18 with total page 414 pages. Available in PDF, EPUB and Kindle. Book excerpt: An important resource that reviews the various infectious diseases that affect bats and bat populations Bats and Human Health: Ebola, SARS, Rabies and Beyond covers existing literature on viral, bacterial, protozoan, and fungal infections of bats and how these infections affect bat populations. The book also offers an overview of the potential for zoonotic transmission of infectious diseases from bats to humans or domestic animals. While most prior publications on the subject have dealt only with bat viral infections, this text closely covers a wide range of bat infections, from viral and bacterial infections to protist and fungal infections. Chapters on viral infections cover rabies, filoviruses, henipaviruses, and other RNA viruses, as well as information on bat virome studies. The book then provides information on bacterial infections–including arthropod-borne and other bacteria that affect bats–before moving on to protist infections, including apicomplexans and kinetoplastids, and fungal infections, including white-nose syndrome, histoplasma capsulatum, and other fungi. Comprehensive in scope, yet another key feature of this book is a searchable database that includes bat species, bat family, bat diet, bat location, type and classification of infecting microbes, and categories of microbes. This vital resource also: Provides a history and comprehensive overview of bat-borne diseases Incorporates information from the World Health Organization, as well as historical data from the National Libraries of Health and infectious disease journals Covers a variety of diseases including viral infections, bacterial infections, protist infections, and fungal infections Written for microbiologist, bat researchers, and conservationists, Bats and Human Health provides a comprehensive exploration of the various types of microbes that affect bats and their potential to affect human populations.