Download When Good Drugs Go Bad PDF Full

When Good Drugs Go Bad

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Publisher : UBC Press
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ISBN : 0774829222
Pages : 320 pages
Rating : 4.4/5 (829 Download)

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Download Free When Good Drugs Go Bad PDF by Dan Malleck Full Book and published by UBC Press. This book was released on 2015-07-15 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the 1800s, opium and cocaine could be easily obtained to treat a range of ailments. Drug dependency, when it occurred, was considered a matter of personal vice. Near the end of the century, attitudes shifted and access to drugs became more restricted. Dan Malleck reveals how different forces converged in the early 1900s to influence lawmakers and set the course for the drug laws that exist today. As this book shows, social concerns about drug addiction had less to do with the long pipe and shadowy den than with lobbying by medical professionals, concern about the morality and future of the nation, and a burgeoning pharmaceutical industry.

Download When Good Drugs Go Bad PDF Full

When Good Drugs Go Bad

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Publisher : University of British Columbia Press
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ISBN : 9780774829199
Pages : 305 pages
Rating : 4.9/5 (192 Download)

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Download Free When Good Drugs Go Bad PDF by Dan Malleck Full Book and published by University of British Columbia Press. This book was released on 2015 with total page 305 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Throughout the 1800s, opium and cocaine could be easily obtained to treat a range of ailments in Canada. Dependency, when it occurred, was considered a matter of personal vice. Near the end of the century, attitudes shifted and access to drugs became more restricted. How did this happen? In this intoxicating history, Dan Malleck examines the conditions that lead to Canada's current drug laws. Drawing on newspaper accounts, medical and pharmacy journals, professional association records, asylum records, physician case books, and pharmacy records, Malleck demonstrates how a number of social, economic, and cultural forces converged in the early 1900s to influence lawmakers and criminalize addiction. His research exposes how social concerns about drug addiction had less to do with the long pipe and shadowy den than with lobbying by medical professionals, concern about the morality and future of the nation, and a growing pharmaceutical industry."--

Download Drugs, Alcohol and Addiction in the Long Nineteenth Century PDF Full

Drugs, Alcohol and Addiction in the Long Nineteenth Century

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Publisher : Routledge
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ISBN : 0429791313
Pages : 2053 pages
Rating : 4.9/5 (791 Download)

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Download Free Drugs, Alcohol and Addiction in the Long Nineteenth Century PDF by Daniel Malleck Full Book and published by Routledge. This book was released on 2021-06-23 with total page 2053 pages. Available in PDF, EPUB and Kindle. Book excerpt: This collection captures key themes and issues in the broad history of addiction and vice in the Anglo-American world. Focusing on the long nineteenth-century, the volumes consider how scientific, social, and cultural experiences with drugs, alcohol, addiction, gambling, and prostitution varied around the world. What might be considered vice, or addiction could be interpreted in various ways, through various lenses, and such activities were interpreted differently depending upon the observer: the medical practitioner; the evangelical missionary; the thrill seeking bon-vivant, and the concerned government commissioner, to name but a few. For example, opium addiction in middle class households resulting from medical treatment was judged much differently than Chinese opium smoking by those in poverty or poor living conditions in North American work camps on the west coast, or on the streets of East London. This collection will assemble key documents representing both the official and general view of these various activities, providing readers with a cross section of interpretations and a solid grounding in the material that shaped policy change, cultural interpretation, and social action.

Download When Good Companies Go Bad: 100 Corporate Miscalculations and Misdeeds PDF Full

When Good Companies Go Bad: 100 Corporate Miscalculations and Misdeeds

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Publisher : ABC-CLIO
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ISBN : 1610694058
Pages : 255 pages
Rating : 4.0/5 (694 Download)

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Download Free When Good Companies Go Bad: 100 Corporate Miscalculations and Misdeeds PDF by Donald W. Beachler Full Book and published by ABC-CLIO. This book was released on 2014-09-09 with total page 255 pages. Available in PDF, EPUB and Kindle. Book excerpt: Covering the entire world of business from heavy industry to the financial houses of Wall Street, this book shines a spotlight on 100 of the most infamous cases of misconduct and malfeasance in corporate history. • Presents cogent and accessible explanations of some of the most important cases involving corporate misconduct of this century in a manner suitable for both general readers and specialists • Supplies information about the financial penalty involved, legal issues, public policy implications, and human stories of the individuals involved for each case • Includes a bibliography for further research, an appendix of the corporations involved, and sidebars containing additional information such as clarifying details and connections to related topics and relevant websites

Download Pleasure and Panic PDF Full

Pleasure and Panic

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Publisher : UBC Press
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ISBN : 9780774867511
Pages : 280 pages
Rating : 4.7/5 (515 Download)

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Download Free Pleasure and Panic PDF by Dan Malleck Full Book and published by UBC Press. This book was released on 2022-05 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pleasure and Panic illustrates how attitudes toward drug and alcohol consumption are complicated by the politics, economics, and culture of their times.

Download Try to Control Yourself PDF Full

Try to Control Yourself

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Publisher : University of British Columbia Press
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ISBN : 9780774822206
Pages : 305 pages
Rating : 4.2/5 (21 Download)

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Download Free Try to Control Yourself PDF by Dan Malleck Full Book and published by University of British Columbia Press. This book was released on 2012 with total page 305 pages. Available in PDF, EPUB and Kindle. Book excerpt: A fascinating history that challenges common assumptions of how the Ontario government attempted to regulate licensed public drinking after the repeal of prohibition.

Download When Good Kids Go Bad PDF Full

When Good Kids Go Bad

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Publisher : PESI Publishing & Media
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ISBN : 1936128136
Pages : 269 pages
Rating : 4.6/5 (128 Download)

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Download Free When Good Kids Go Bad PDF by Steven T. Olivas Full Book and published by PESI Publishing & Media. This book was released on 2012 with total page 269 pages. Available in PDF, EPUB and Kindle. Book excerpt: Informative, artful, and fun, When Good Kids Go Bad: Effective Solutions for Problem Behaviors takes readers inside the minds of our troubled kids and teens. Whether they are mildly irritating or well out of control, readers will leave armed with a broad range of proven techniques to curb negative behaviors and encourage positive ones. Therapists, parents, teachers, and all professionals interacting with these kids will have their questions answered and be given clear instructions on how to begin the road to behavioral and emotional change. Interventions are detailed for use in the home, the classroom, and/or the therapy office so that all adults can begin to march in stride and provide the structure needed to facilitate maximum growth. From the diagnostic process to medication interventions, no stone is left unturned.

Download Strange Trips PDF Full

Strange Trips

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Publisher : McGill-Queen's Press - MQUP
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ISBN : 0773556524
Pages : pages
Rating : 4.3/5 (556 Download)

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Download Free Strange Trips PDF by Lucas Richert Full Book and published by McGill-Queen's Press - MQUP. This book was released on 2019-02-28 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Examining the boundaries between recreational and medicinal drugs in the eyes of the public and the law.

Download Adverse Drug Reactions PDF Full

Adverse Drug Reactions

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Publisher : Springer Science & Business Media
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ISBN : 9783642006630
Pages : 556 pages
Rating : 4.6/5 (639 Download)

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Download Free Adverse Drug Reactions PDF by Jack Uetrecht Full Book and published by Springer Science & Business Media. This book was released on 2009-12-18 with total page 556 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides the current state of knowledge of basic mechanisms of adverse drug reactions (ADRs). The main focus is on idiosyncratic drug reactions because they are the most difficult to deal with. It starts with a general description of the major targets for ADRs followed by a description of what are presently believed to be mediators and biochemical pathways involved in idiosyncratic drug reactions. There is also a description of several examples of ADRs that serve to illustrate specific aspects of ADR mechanisms. Eventually the book shows that ultimately better methods are needed to predict which drug candidates are likely to cause ADRs and which patients are at increased risk. But at present research seems to be far from this goal.

Download Pharmacogenetics PDF Full

Pharmacogenetics

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Publisher : Oxford University Press
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ISBN : 0195341511
Pages : 448 pages
Rating : 4.5/5 (341 Download)

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Download Free Pharmacogenetics PDF by Wendell Weber Full Book and published by Oxford University Press. This book was released on 2008-04-02 with total page 448 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genes are important modifiers of the human response to drugs, hormones, and toxins. In this second edition of 'Pharmacogenetics', Weber brings together laboratory methods and epidemiologic studies in defining the role of heredity in human drug response.

Download Post-genomic Approaches in Drug and Vaccine Development PDF Full

Post-genomic Approaches in Drug and Vaccine Development

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Publisher : CRC Press
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ISBN : 1000795713
Pages : 451 pages
Rating : 4.0/5 (795 Download)

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Download Free Post-genomic Approaches in Drug and Vaccine Development PDF by Kishore R. Sakharkar Full Book and published by CRC Press. This book was released on 2022-09-01 with total page 451 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the past decade, genome sequencing projects and the associated efforts have facilitated the discovery of several novel disease targets and the approval of several innovative drugs. To further exploit this data for human health and disease, there is a need to understand the genome data itself in detail, discover novel targets, understand their role in physiological pathways and associated diseases, with the aim to translate these discoveries to clinical and preventive medicine. It is equally important to understand the labors and limitations in integrating clinical phenotypes with genomic, transcriptomic, proteomic and metabolomic approaches. T

Download Atkinson's Principles of Clinical Pharmacology PDF Full

Atkinson's Principles of Clinical Pharmacology

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Publisher : Academic Press
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ISBN : 0128198842
Pages : 762 pages
Rating : 4.8/5 (198 Download)

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Download Free Atkinson's Principles of Clinical Pharmacology PDF by Shiew-Mei Huang Full Book and published by Academic Press. This book was released on 2021-10-16 with total page 762 pages. Available in PDF, EPUB and Kindle. Book excerpt: Atkinson’s Principles of Clinical Pharmacology, Fourth Edition is the essential reference on the pharmacologic principles underlying the individualization of patient therapy and contemporary drug development. This well-regarded survey continues to focus on the basics of clinical pharmacology for the development, evaluation and clinical use of pharmaceutical products while also addressing the most recent advances in the field. Written by leading experts in academia, industry, clinical and regulatory settings, the fourth edition has been thoroughly updated to provide readers with an ideal reference on the wide range of important topics impacting clinical pharmacology. Presents the essential knowledge for effective practice of clinical pharmacology Includes a new chapter and extended discussion on the role of personalized and precision medicine in clinical pharmacology Offers an extensive regulatory section that addresses US and international issues and guidelines Provides extended coverage of earlier chapters on transporters, pharmacogenetics and biomarkers, along with further discussion on "Phase 0" studies (microdosing) and PBPK

Download Leveraging Pharmacovigilance Data Mining with “The Patient” in Mind PDF Full

Leveraging Pharmacovigilance Data Mining with “The Patient” in Mind

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Publisher : Frontiers Media SA
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ISBN : 2832500625
Pages : 120 pages
Rating : 4.2/5 (5 Download)

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Download Free Leveraging Pharmacovigilance Data Mining with “The Patient” in Mind PDF by Maxine Deborah Gossell-Williams Full Book and published by Frontiers Media SA. This book was released on 2022-09-23 with total page 120 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download Molecular Computing and Bioinformatics PDF Full

Molecular Computing and Bioinformatics

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Publisher : MDPI
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ISBN : 3039211951
Pages : 390 pages
Rating : 4.9/5 (211 Download)

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Download Free Molecular Computing and Bioinformatics PDF by Xiangxiang Zeng Full Book and published by MDPI. This book was released on 2019-07-11 with total page 390 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text will provide the most recent knowledge and advances in the area of molecular computing and bioinformatics. Molecular computing and bioinformatics have a close relationship, paying attention to the same object but working towards different orientations. The articles will range from topics such as DNA computing and membrane computing to specific biomedical applications, including drug R&D and disease analysis.

Download Systems Biology PDF Full

Systems Biology

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Publisher : John Wiley & Sons
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ISBN : 3527696164
Pages : 600 pages
Rating : 4.7/5 (696 Download)

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Download Free Systems Biology PDF by Jens Nielsen Full Book and published by John Wiley & Sons. This book was released on 2017-03-21 with total page 600 pages. Available in PDF, EPUB and Kindle. Book excerpt: Comprehensive coverage of the many different aspects of systems biology, resulting in an excellent overview of the experimental and computational approaches currently in use to study biological systems. Each chapter represents a valuable introduction to one specific branch of systems biology, while also including the current state of the art and pointers to future directions. Following different methods for the integrative analysis of omics data, the book goes on to describe techniques that allow for the direct quantification of carbon fluxes in large metabolic networks, including the use of 13C labelled substrates and genome-scale metabolic models. The latter is explained on the basis of the model organism Escherichia coli as well as the human metabolism. Subsequently, the authors deal with the application of such techniques to human health and cell factory engineering, with a focus on recent progress in building genome-scale models and regulatory networks. They highlight the importance of such information for specific biological processes, including the ageing of cells, the immune system and organogenesis. The book concludes with a summary of recent advances in genome editing, which have allowed for precise genetic modifications, even with the dynamic control of gene expression. This is part of the Advances Biotechnology series, covering all pertinent aspects of the field with each volume prepared by eminent scientists who are experts on the topic in question.

Download Systems Biology PDF Full

Systems Biology

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Publisher : John Wiley & Sons
Release Date :
ISBN : 3527335587
Pages : 426 pages
Rating : 4.7/5 (335 Download)

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Download Free Systems Biology PDF by Jens Nielsen Full Book and published by John Wiley & Sons. This book was released on 2017-05-30 with total page 426 pages. Available in PDF, EPUB and Kindle. Book excerpt: Comprehensive coverage of the many different aspects of systems biology, resulting in an excellent overview of the experimental and computational approaches currently in use to study biological systems. Each chapter represents a valuable introduction to one specific branch of systems biology, while also including the current state of the art and pointers to future directions. Following different methods for the integrative analysis of omics data, the book goes on to describe techniques that allow for the direct quantification of carbon fluxes in large metabolic networks, including the use of 13C labelled substrates and genome-scale metabolic models. The latter is explained on the basis of the model organism Escherichia coli as well as the human metabolism. Subsequently, the authors deal with the application of such techniques to human health and cell factory engineering, with a focus on recent progress in building genome-scale models and regulatory networks. They highlight the importance of such information for specific biological processes, including the ageing of cells, the immune system and organogenesis. The book concludes with a summary of recent advances in genome editing, which have allowed for precise genetic modifications, even with the dynamic control of gene expression. This is part of the Advances Biotechnology series, covering all pertinent aspects of the field with each volume prepared by eminent scientists who are experts on the topic in question.

Download Principles of Clinical Pharmacology PDF Full

Principles of Clinical Pharmacology

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Publisher : Academic Press
Release Date :
ISBN : 0123854725
Pages : 652 pages
Rating : 4.3/5 (854 Download)

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Download Free Principles of Clinical Pharmacology PDF by Arthur J. Atkinson, Jr. Full Book and published by Academic Press. This book was released on 2012-09-18 with total page 652 pages. Available in PDF, EPUB and Kindle. Book excerpt: Principles of Clinical Pharmacology is a successful survey covering the pharmacologic principles underlying the individualization of patient therapy and contemporary drug development. This essential reference continues to focus on the basics of clinical pharmacology for the development, evaluation, and clinical use of pharmaceutical products while also addressing the most recent advances in the field. Written by leading experts in academia, industry, clinical and regulatory settings, the third edition has been thoroughly updated to provide readers with an ideal reference covering the wide range of important topics impacting clinical pharmacology as the discipline plays an increasingly significant role in drug development and regulatory science. The Third Edition has been endorsed by the American Society for Clinical Pharmacology and Therapeutics Includes new chapters on imaging and the pharmacogenetic basis of adverse drug reactions Offers an expanded regulatory section that addresses US and international issues and guidelines Provides extended coverage of earlier chapters on transporters, pharmacogenetics and biomarkers and also illustrates the impact of gender on drug response Presents a broadened discussion of clinical trials from Phase 1 to incorporate Phases II and III